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Home>Products>Raw Steroid Powders>Raw Steroid Powders Megestrol Acetate CAS 595-33-5 Progesterone Hormones

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  • Raw Steroid Powders Megestrol Acetate CAS 595-33-5 Progesterone Hormones
  • Raw Steroid Powders Megestrol Acetate CAS 595-33-5 Progesterone Hormones

Raw Steroid Powders Megestrol Acetate CAS 595-33-5 Progesterone Hormones

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Zhuhaishi Shaohui Technology Co.,ltd

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  • Zhuhaishi Shaohui Technology Co.,ltd2020-07-10 09:46:19
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Product Details

CAS: 595-33-5 MF: C24H32O4 MW: 384.51
EINECS: 209-864-5 Purity: 99%min. Properties: Powder
Payment: T/T, Western Union, MoneyGram, Bitcoin Delivery time: Within 24 hours Delivery Mode: EXPRESS Door to Door

Product Description

 

Raw Steroid Powders Megestrol Acetate CAS 595-33-5 Progesterone Hormones

 

Megestrol acetate

Product Name: Megestrol acetate 
Synonyms: 17-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;17-alpha-acetoxy-6-dehydro-6-methylprogesterone;17alpha-Acetoxy-6-dehydro-6-methylprogesterone;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione17-acetate;5071;6-dehydro-6-methyl-17-alpha-acetoxyprogesterone;6-Dehydro-6-methyl-17alpha-acetoxyprogesterone 
CAS: 595-33-5 
MF: C24H32O4 
MW: 384.51 
EINECS: 209-864-5 

Chemical Properties Crystalline Solid 
Usage Progestogen;Progesterone receptor agonist 
Usage Orally active progestogen; formerly used in combinations as oral contraceptive 

 

Megestrol Acetate Description :

 

Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.


Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.
Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body.

 

As an example, one study in men with benign prostatic hyperplasia who were treated with 120-160 mg of megestrol acetate per day for 3 to 11 days found average decreases in AR quantity of 73% and 86% in the cytoplasm and nucleus of prostatic cells, respectively.These actions are likely the result of a strong activation of the PR, which suppresses the secretion of the gonadotropins-peptide hormones responsible for signaling the body to produce not only progesterone but also the androgens and the estrogens-from the pituitary gland as a form of negative feedback inhibition, and hence downregulates the hypothalamic-pituitary-gonadal (HPG) axis, resulting in decreased levels of the sex hormones and their associated enzymes, carriers (e.g., sex hormone-binding globulin), and receptors.It is the antiandrogenic  and antiestrogenic effects of megestrol acetate mediated by suppression of the HPG axis that are believed to be largely responsible for its beneficial effects against androgen and estrogen-sensitive cancers, respectively.

 

Megestrol Acetate Application :

  • Mainly used for short-acting oral contraceptives, also can be used for intramuscular injection of long-acting contraceptives.
  • For the treatment of dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma
Related Female Hormone Steroids:
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Estradiol valerate Estriol Hydrocortisone acetate
Estradiol benzoate Nylestriol Meprednisone
Estradiol cypionate Diethylstilbestrol Prednisone acetate
Estradiol enantate HEXESTROL Bentelan
Ethynyl estradiol Progesterone Betamethasone
Algestone acetophenide Medroxyprogesterone acetate Clobetasol propionate
Ethisterone Norethindrone Halobetasol propionate
19-Norethindrone acetate Mifepristone Deflazacort
Norethisterone Enanthate Methyldienedione Tazarotene
Ethynodiol diacetate Eplerenone Ecdysone
Pregnenolone acetate Levonorgestrel Desloratadine
Lynestrenol Allylestrenol Prednisolone phosphate sodium
Chlormadinone acetate Dienogestrel Fluorometholone Acetate
Cyproterone acetate Drospirenone Dexamethasone Acetate
Megestrol acetate Pregnenolone Dexamethasone Sodium Phosphate
Melengestrol acetate Mometasone furoate Dexamethasone palmitate
Betamethasone acetate Beclomethasone dipropionate Fluocinolone acetonide
Betamethasone Dipropionate Betamethasone 17-valerate  

 
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,WU,MoneyGram,Paypal Available.
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your orders further new situation at any time.
6. Package: Professional packing with professional materials.
 
Our advantage:
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you; 
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we e sure they can satisfy you well enough; 
3. Package: Professional packing with professional materials 
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days. 
5. Service: Best Service with after-sales service and consultation

 

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TACROLIMUS 4-Androsten-3b-ol-17-one Contact: Ivy Young
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Estrone Estradiol benzoate



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