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High Estrogenic Potency Ethynyl Estradiol CAS 57-63-6 for Oral Contraceptive
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Zhuhaishi Shaohui Technology Co.,ltd2020-07-10 09:46:19
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Product Details
| CAS: | 57-63-6 | MF: | C20H24O2 | MW: | 296.4 |
| EINECS: | 200-342-2 | Purity: | 99%min. | Properties: | Powder |
| Payment: | T/T, Western Union, MoneyGram, Bitcoin | Delivery time: | Within 24 hours | Delivery Mode: | EXPRESS Door to Door |
Product Description
High Estrogenic Potency Ethynyl Estradiol CAS 57-63-6 for Oral Contraceptive
Ethynyl estradiol
Product Name: Ethynyl estradiol
Synonyms: NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL;LYNORAL;17ALPHA-ETHYNYL-DELTA1,3,5(10)-ESTRA-TRIENE-3,17BETA-DIOL;17ALPHA-ETHYNYLESTRADIOL;17ALPHA-ETHINYLESTRADIOL
CAS: 57-63-6
MF: C20H24O2
MW: 296.4
EINECS: 200-342-2
Chemical Properties Off-White to Light-Yellow Crystalline Powder
Usage A metabolite of 17a-Ethynylestradiol
Usage A synthetic steroid with high oral estrogenic potency
Usage estrogen, plus progestogen as oral contraceptive
General Description Fine white to creamy white powder. A synthetic steroid. Used in combination with progestogen as an oral contraceptive.
Air & Water Reactions Air and light sensitive . Insoluble in water.
Reactivity Profile Ethynyl estradiol may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to generate gaseous hydrogen.
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition Ethynyl estradiol emits acrid smoke and fumes.
Fire Hazard The flash point data for Ethynyl estradiol are not available. Ethynyl estradiol is probably combustible.
Ethynyl estradiol Description:
Ethinyl estradiol (EE) also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl œstradiol, is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.
Transdermal ethinyl estradiol carries a greater risk of clot formation and venous thromboembolism than naturally occurring 17β-estradiol, which some have theorized to be related to different amounts of hepatic metabolism after absorption. The same contraindications and precautions apply for EE as with other estrogen medications.
Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.
EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.
The major concern with unopposed estrogen (without progestogen) is of endometrial cancer. As such, the medication is generally prescribed with progesterone in the setting of birth control
Ethynyl estradiol Specifications:
|
TEST ITEMS |
SPECIFICATION |
RESULTS |
|
Description |
: White or Almost White Crystalline Powder |
white powder |
|
Identification |
: A.B. |
Positive |
|
Assay |
: 97.0~102.0% |
99.3% |
|
Specific Rotation |
: +101°~+105° |
+102.6° |
|
Loss On Drying |
: 1.0%max |
0.27% |
|
Melting Point |
: 153~157°C |
153.0~155.0°C |
|
Organic Volatile Impurities |
: meets the requirement. |
Conforms |
|
Related Substances |
: meets the requirement. |
Conforms |
|
Residual Solvents |
: meets the requirement. |
Conforms |
|
Particle Size |
: 100% ≤ 20 microns |
Conforms |
|
Conclusion |
The specification conform with USP30 standard |
|
| Estradiol | Estrone | Hydrocortisone |
| Estradiol valerate | Estriol | Hydrocortisone acetate |
| Estradiol benzoate | Nylestriol | Meprednisone |
| Estradiol cypionate | Diethylstilbestrol | Prednisone acetate |
| Estradiol enantate | HEXESTROL | Bentelan |
| Ethynyl estradiol | Progesterone | Betamethasone |
| Algestone acetophenide | Medroxyprogesterone acetate | Clobetasol propionate |
| Ethisterone | Norethindrone | Halobetasol propionate |
| 19-Norethindrone acetate | Mifepristone | Deflazacort |
| Norethisterone Enanthate | Methyldienedione | Tazarotene |
| Ethynodiol diacetate | Eplerenone | Ecdysone |
| Pregnenolone acetate | Levonorgestrel | Desloratadine |
| Lynestrenol | Allylestrenol | Prednisolone phosphate sodium |
| Chlormadinone acetate | Dienogestrel | Fluorometholone Acetate |
| Cyproterone acetate | Drospirenone | Dexamethasone Acetate |
| Megestrol acetate | Pregnenolone | Dexamethasone Sodium Phosphate |
| Melengestrol acetate | Mometasone furoate | Dexamethasone palmitate |
| Betamethasone acetate | Beclomethasone dipropionate | Fluocinolone acetonide |
| Betamethasone Dipropionate | Betamethasone 17-valerate |
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