Sildenafil Viagra / Sildenafil Citrate Sex Enhancement Powder 521-11-9

Sildenafil Viagra / Sildenafil Citrate Sex Enhancement Powder

Sildenafil CAS: 139755-83-2

Sildenafil Assay: 99% min.

Sildenafil Molecular formula: C22H30N6O4S

Sildenafil Molecular weight: 474.58

Sildenafil Packing: 1kg net/foil bag, 5kg/drum.

Sildenafil Delivery: Express courier.

Sildenafil Character: White or almost white crystalline powder, odorless, bitter astringent taste, insoluble in water and ethanol.

During sexual stimulation, the penis non-adrenergic non-cholinergic neuronal nitric oxide synthase and vascular endothelial L-arginine catalyzed synthesis of nitric oxide, which activate guanylate cyclase to make cyclic monophosphate guanosine synthesis, thereby giving rise to smooth muscle relaxation of corpus cavernosum smooth muscle, and small arteries, cavernous blood into the penis, so that penile erection. Meanwhile cyclic guanosine monophosphate and by hydrolysis of phosphodiesterase.

Thus, in theory, both to improve the guanylate cyclase activity, or inhibiting phosphodiesterase activity, can increase the cGMP level, it helps penile corpus cavernosum smooth muscle and smooth muscle of small arteries relaxation. Viagra (sildenafil) is through inhibition of the hydrolytic activity of phosphodiesterase to increase cGMP levels without affecting cAMP, thereby increasing the sexual stimulation of nitric oxide synthase / cyclic guanosine monophosphate waterfall effect, so cavernous smooth muscle relaxation, to achieve the purpose of treatment of erectile dysfunction.

For most patients, the recommended dose is 50mg, in about 1 hour before sexual activity taking; but any time before sexual activity within 0.5 to 4 hours can be taken. Based on the efficacy and tolerability, the dose can be increased to 100 mg (the maximum recommended dose) or decreased to 25 mg. Maximum daily doses of 1.

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