Local Anesthetic Raw Powder Levobupivacaine Hydrochloride 27262-48-2

Local Anesthetic Raw Powder Levobupivacaine Hydrochloride 27262-48-2


1. Levobupivacaine Hydrochloride Description:

Name:Levobupivacaine hydrochloride
Levobupivacaine hydrochloride synonyms:Timtec-bb sbb001337;(s)-(-)-bupivacaine hcl;
(s)-(-)-bupivacaine hydrochloride;(s)-(-)-1-n-butyl-2,6-dimethyl-2-piperidincarboxanilid hydrochloride;
(s)-(-)-1-butyl-2-(2,6-xylylcarbamoyl)-piperidine hydrochloride;S-(-)-1-butyl-2,6-pipecoloxylidide hydrochloride;
(s)-1-butyl-2,6-piperidinecarboxamidemonohydrochloride;
(s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride
Levobupivacaine hydrochloride CAS:27262-48-2
Levobupivacaine hydrochloride MF:C18H29ClN2O
Levobupivacaine hydrochloride MW:324.89
Levobupivacaine hydrochloride product categories:Pharmaceutical raw materials;Active pharmaceutical ingredients
Levobupivacaine hydrochloride chemical properties:White crystalline powder
Levobupivacaine hydrochloride usage:Anesthetic;Na+ channel inhibitor.
Packing:25kg/drum or as required

2. Levobupivacaine Hydrochloride Usage:
Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer
of bupivacaine.
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and
transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia.

In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.

3. Levobupivacaine Hydrochloride Specification:
Description White crystalline powder.
Solubility Freely soluble in water and in alcohol; slightly soluble
in chloroform and in acetone.
IdentifIcation A: By IR, To match with working standard
B: By UV, To match with working standard
C: Chloride test, To Matching with the standard
PH 4.5 ~ 6.0
Water 4.0%~6.0%
Residue on ignition ≤ 0.1%
Heavy metals ≤ 0.001%
Limit of residual solvents Should be to match with the standard
Chromatographic purity Should be to match with the standard
Assay 98.5~101.5%
(on the anhydrous basis.)

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