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Home>Products>Local Anesthetic Drugs>Pharmaceutical Grade Local Anesthetic Drugs Tetracaine HCl CAS136-47-0

Pharmaceutical Grade Local Anesthetic Drugs Tetracaine HCl CAS136-47-0
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136-47-0
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Zhuhaishi Shaohui Technology Co.,ltd2020-07-10 09:46:19
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Product Details
EINECS: | 205-248-5 | CAS NO.: | 136-47-0 | Molecular formula: | C15H25ClN2O2 |
Molecular Weight: | 300.82 | Use: | local anesthetics | Payment terms: | Western Union, MoneyGram, T/T,Bitcoin |
Delivery: | EMS, DHL, FedEx, Express courier. | my website: | www.steriodshow.com | appreance: | white powder |
Product Description
Pharmaceutical Grade Local Anesthetic Drugs Tetracaine HCl CAS136-47-0
Tetracaine HCl Names: L AND OCAIN HYDROCHLORIDE; INTERCAIN HYDROCHLORIDE; MEETHOBALM HYDROCHLORIDE; 2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE; 2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE; 4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE; 4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE; 4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
Tetracaine HCl CAS No.: 136-47-0
Tetracaine HCl Molecular formula: C15H25ClN2O2
Tetracaine HCl Molecular weight: 300.82
Tetracaine HCl EINECS: 205-248-5
Tetracaine HCl Assay: 99%
Tetracaine HCl Packing: 25kg/drum
Tetracaine HCl Appearance: White crystalline powder
Tetracaine HCl Melting point: 149°C
Tetracaine HCl Assay: 99%
Tetracaine HCl Grade: Pharmaceutical Grade
Tetracaine HCl Storage: Closed, confined and shading preservation
Tetracaine HCl Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
Test Items | Specification | Test Results |
Appearance | Fine, white, crystalline, odorless powder | confirm |
Identification | ABC in Pass | confirm |
Solubility |
Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene |
confirm |
USP Reference standards | USP Tetracaine Hydrochloride RS. USP Endotoxin RS. | confirm |
Melting point | 145~150 degree | 146.0~147.5 degree |
Chromatographic purity | In Pass | confirm |
Related substance | Not more than the reference solution 0.05% | confirm |
Heavy metals | ≤10ppm | confirm |
PH | 4.5-6.5 | 5.8 |
Residue on ignition | ≤0.10% | 0.05% |
Loss on Drying | ≤ 0.5% | 0.19% |
Assay | 98.0 -101.0% | 100.1% |
Conclusion | Confirms USP 32 |
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a
potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an
antipruritic,
and it has been used in spinal anesthesia.In biomedical research, tetracaine is used to alter the
function of calcium release channels (ryanodine receptors) that control the release of calcium from
intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations,
tetracaine causes an initial inhibition of spontaneous calcium release events, while at high
concentrations, tetracaine blocks release completely.
Local Anesthetic Series | |
Linocaine HCl | CAS No.: 6108-05-0 |
Propitocaine HCl | CAS No.: 1786-81-8 |
Tetracaine HCl | CAS No.: 136-47-0 |
Benzocaine | CAS No.: 94-09-7 |
Prilocaine | CAS No.: 721-50-6 |
Procaine | CAS No.: 59-46-1 |
Pramoxine HCl | CAS No.: 637-58-1 |
Procainamide HCl | CAS No.: 614-39-1 |
Ropivacaine HCl | CAS No.: 98717-15-8 |
Dibucaine HCl | CAS No.: 61-12-1 |
Bupivacaine HCl | CAS No.: 14252-80-3 |
Levobupivacaine HCl | CAS No.: 27262-48-2 |
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