Pharmaceutical Grade Local Anesthetic Drugs Tetracaine HCl CAS136-47-0

Pharmaceutical Grade Local Anesthetic Drugs Tetracaine HCl CAS136-47-0

Tetracaine HCl Names: L AND OCAIN HYDROCHLORIDE; INTERCAIN HYDROCHLORIDE; MEETHOBALM HYDROCHLORIDE; 2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE; 2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE; 4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE; 4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE; 4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL

Tetracaine HCl CAS No.: 136-47-0

Tetracaine HCl Molecular formula: C15H25ClN2O2

Tetracaine HCl Molecular weight: 300.82

Tetracaine HCl EINECS: 205-248-5

Tetracaine HCl Assay: 99%

Tetracaine HCl Packing: 25kg/drum

Tetracaine HCl Appearance: White crystalline powder

Tetracaine HCl Melting point: 149°C
Tetracaine HCl Assay: 99%
Tetracaine HCl Grade: Pharmaceutical Grade
Tetracaine HCl Storage: Closed, confined and shading preservation
Tetracaine HCl Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a

potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an

antipruritic,

and it has been used in spinal anesthesia.In biomedical research, tetracaine is used to alter the

function of calcium release channels (ryanodine receptors) that control the release of calcium from

intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations,

tetracaine causes an initial inhibition of spontaneous calcium release events, while at high

concentrations, tetracaine blocks release completely.

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