Steroid Betamethasone 21- Acete Anti - inflammation Hormone Betamethasone

Steroid Betamethasone 21-Acete Anti-inflammation Hormone Betamethasone Acetate

1. Quick Detail:

English name: betamethasone 21-acetate
English Name: Betamethasone Acetate; (8xi, 10xi, 11beta, 13xi, 16beta) -9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate; (11beta, 16beta) -9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
CAS: 987-24-6
EINECS Number: 213-578-6
Formula: C24H31FO6
MW: 434.4977
Molecular Structure:

Density: 1.3g / cm3
Melting point: 200-220 ℃ (dec.)
Boiling point: 579.4 ° C at 760 mmHg
Flash Point: 304.2 ° C
Vapor Pressure: 7.75E-16mmHg at 25 ° C

Assay:98%

Appearance:White crystalline powder


2. Description:

Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cause water retention. It is applied as a topical cream, ointment, foam, lotion or gel to treat itching. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection for itching from various ailments, including allergic reactions to poison ivy and similar plants.

It is on the World Health Organizations List of Essential Medicines, a list of the most important medication needed in a basic health system.

3. Applications:

Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking fromeczema. It is used as a treatment for local psoriasis, as betamethasone dipropionate and salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is used orally and via injection with the same indications as other steroids. Many betamethasone-based pharmaceuticals, include the steroid as the valerate ester.

In a randomized controlled trial Betamethasone was shown to reduce some of the ataxia symptoms associated with Ataxia Telangiectasia (A-T) by 28-31%.

Alternative medical approach for large microcystic CCAMs – Betamethasone therapy

Betamethasone is also used prior to delivery of a preterm baby to help prepare the lung for breathing.

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