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Pharmaceutical Anastrozole Anti Estrogen Steroids Raw powder
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Zhuhaishi Shaohui Technology Co.,ltd2020-07-10 09:46:19
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Product Details
Product name: | Anastrozole | Other name: | Arimidex | CAS NO.: | 53-41-8 |
Purity: | 99% | Delivery: | door-to-door delivery | Grade: | Pharmaceutical Grade |
Product Description
Description:
Anastrozole
Alias: Arimidex
CAS No: 120511-73-1
MF: C17H19N5
MW: 293.37
Purity: 98%
Solubility: Insoluble
Appearance: white powder.
Grade Standard:Medicine Grade
Anastrozole profile:
Anastrozole is also called Arimidex. It is a type of hormone therapy called an aromatase inhibitor. Anastrozoles treats breast cancer in women who have had their menopause.
Arimidex is the aromatase inhibitor of choice. Arimidexs mechanism of action - blocking conversion of aromatizable steroids to estrogen - is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.
Anastrozole Application:
ARIMIDEX is approved for adjuvant treatment (treatment following surgery with or without radiation) of postmenopausal women with hormone receptor-positive early breast cancer.
ARIMIDEX is approved for the initial treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer and for the treatment of postmenopausal women with advanced breast cancer that has progressed following treatment with tamoxifen. Patients with hormone receptor-negative disease and patients who did not previously respond to tamoxifen therapy rarely responded to ARIMIDEX.
Anastrozoles can also Help Shrink Tumor and Slow Their Growth. Arimidex is a hormonal therapy used to treat breast cancer in women who have been through the menopause. Hormones are substances produced naturally in the body. They act as chemical messengers and help control the activity of cells and organs. Hormonal therapies work by interfering with the production or action of particular hormones in the body.
Anastrozoles has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism.
Some athletes and body builders use anastrozoles as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention.
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Analysis list:
Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
Solubility | Freely soluble in methanol,acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrile |
Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0ºC | 82.5~83.2ºC |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.8% |
Storage | Cool and dry | |
Conclusion | It complies to USP32 . |
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Pharmaceutical Anastrozole Anti Estrogen Steroids Raw powder Images |
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