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Pharmaceutical API Anabolic Androgenic Steroids Spironolactone CAS 52-01-7
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Product Details
| CAS: | 52-01-7 | MF: | C24H32O4S | MW: | 416.57 |
| EINECS: | 200-133-6 | Purity: | 99%min. | Properties: | Powder |
| Payment: | T/T, Western Union, MoneyGram, Bitcoin | Delivery time: | Within 24 hours | Delivery Mode: | EXPRESS Door to Door |
Product Description
Anabolic Androgenic Steroids Spironolactone CAS 52-01-7 Pharmaceutical API
Spironolactone
CAS: 52-01-7
MF: C24H32O4S
MW: 416.57
EINECS: 200-133-6
ITEMS SPECIFICATION
Appearance almoste white crystalline powder
Melting point 198-209°C
Specific rotation between -33°And- 37°
Indentificaftion meet the requirements
Relate substances sum of impurities
(except canrenone) ≤ 1.0%
Canrenone ≤ 1.0%
Sum of impurities+canrenone ≤ 1.0%
Chromium ≤ 50ppm
Loss on drying ≤ 0.5%
Sulphated ash ≤ 0.1%
Heavy Metal ≤ 0.002%
Limit of mercapto compounds Conform
Ordinary impurities Conform
Assay (on the dried basis) 97%~102.0%
Chemical Properties White to Off White Solid
Usage It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia
Usage diuretic, aldosterone antagonist
Biological Activity Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis.
Spironolactone Specification:
|
Test Items |
Specification |
Test Results |
|
Appearance |
Almost white crystalline powder |
Almost white crystalline powder |
|
Identification |
Meet the requirements |
Meet the requirements |
|
Melting range |
198℃~209℃ Between 198℃ and 209℃ |
205.0℃~207.0℃ |
|
Specific rotation |
-33°~-37° Between -33° and -37° |
-35° |
|
Loss on drying |
≤0.5% Not more than 0.5% |
0.2% |
|
Limit of mercapto compounds |
Meet the requirements |
Meet the requirements |
|
Ordinary impurities |
Meet the requirements |
Meet the requirements |
|
Organic volatile impurities |
Meet the requirements |
Meet the requirements |
|
Assay(on the dried basis) |
97.0%~103.0%(C24H32O4S) Between 97.0% and 103.0% |
98.99% |
|
Conclusion |
Meet the requirements of USP29 |
|
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